Only verified researchers can join ResearchGate and send messages to other members. View the profiles of people named Nina Wagner. A comparison of the natural history of oxaliplatin- and paclitaxel-induced neuropathy (NCCTG N08C1, N08CB/Alliance). Comparative effectiveness of anthracycline-containing chemotherapy in United States veterans age 80 and older with diffuse large B-cell lymphoma, Mature Follow up from a Phase 2 Study of PI3K-Delta Inhibitor Idelalisib in Patients with Double (Rituximab and Alkylating agent)-Refractory Indolent B-Cell Non-Hodgkin Lymphoma (iNHL), High Frequency of Identical Lymphoma Clones Detected in Pre-Treatment Tumor and Plasma from Untreated Patients with HIV-Associated Lymphomas: Prospective Multicenter Trial of the AIDS Malignancy Consortium (AMC 064), Long-Term Follow-up of a Phase 1 Trial of Idelalisib (ZYDELIG®) in Combination with Bendamustine (B), Bendamustine/Rituximab (BR), Fludarabine (F), Chlorambucil (Chl), or Chlorambucil/Rituximab (ChlR) in Patients with Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL), Durable Responses Following Treatment with the PI3K-Delta Inhibitor Idelalisib in Combination with Rituximab, Bendamustine, or Both, in Recurrent Indolent Non-Hodgkin Lymphoma: Phase I/II Results, Progressive Multifocal Leukoencephalopathy Associated With Brentuximab Vedotin Therapy A Report of 5 Cases from the Southern Network on Adverse Reactions (SONAR) Project, Limited Utility of Routine Surveillance Imaging for Classical Hodgkin Lymphoma Patients in First Complete Remission, Management options for established chemotherapy-induced peripheral neuropathy. IPAD PRO - DATEN VERSION: IOS 11.4.1 MODELLNAME (12.9 Zoll) APPLE ID: hermann.sen.rhammer@icloud.com PASSWORT: Rheinpfalz33 WLAN PASSWORT: qeqe86we WLAN PASSWORT - in „Einst.“: ejg5bf3mockta IPAD AIR - DATEN (iPad von Anni) VERSION: 12.4.9 APPLE ID: anni.rhammer@icloud.com PASSWORT: Rheinpfalz33 WLAN PASSWORT: qeqe86we WLAN … FDA granted... BACKGROUND AMC 048: modified CODOX-M/IVAC-rituximab is safe and effective for HIV-associated Burkitt lymphoma, 5-year follow-up of a randomized controlled trial of immediate versus delayed zoledronic acid for the prevention of bone loss in postmenopausal women with breast cancer starting letrozole after tamoxifen: N03CC (Alliance) trial: Letrozole-Associated Bone Loss Prevention, Patient-reported outcomes data from a phase 2 study of idelalisib in patients with refractory indolent B-cell non-hodgkin lymphoma (iNHL), Safety and Benefit of Discontinuing Statin Therapy in the Setting of Advanced, Life-Limiting Illness: A Randomized Clinical Trial. John Cino and Nina Ezrati Wagner Production Idelalisib is a first-in-class, selective, oral inhibitor of PI3Kδ. Background: PI3K-delta signaling is critical for activation, proliferation and survival of B cells, plays a role in homing and retention in lymphoid tissues, and is hyperactive in many B-cell malignancies. Clinical course of patients with cisplatin (CDDP)-associated neuropathy compared to other neurotoxic chemotherapy. Idelalisib is a first-in-class, selective, oral inhibitor of PI3Kδ that has shown considerable monotherapy activity in pts with heavily pretreated CLL. The current study was undertaken to determine whether upfront versus delayed treatment with zoledronic acid (ZA) impacted bone loss. Background: PI3K-delta signaling is critical for proliferation, survival, homing and tissue retention of malignant B cells. : A pilot randomized placebo-controlled trial. 79 likes. Fifty patients, sched... We assessed the incidence, prognostic features, and outcomes associated with transformation of follicular lymphoma (FL) among 2652 evaluable patients prospectively enrolled in the National LymphoCare Study. 'Mild und Leise' (Liebestod) - Tristan und IsoldeNina StemmeDaniel Harding?Truly magnificent singing.Previously uploaded by jiminy22221. Home / Find a fitter / Nina Wagner. A Phase 2 Study of Inotuzumab Ozogamicin and Rituximab, Followed by Autologous Stem Cell Transplantation in Patients with Relapsed/Refractory Diffuse Large B-Cell Lymphoma. In an attempt to alleviate this problem, clinicians and patien... To provide evidence-based guidance on the optimum prevention and treatment approaches in the management of chemotherapy-induced peripheral neuropathies (CIPN) in adult cancer survivors. Clinicians are cognizant of the negative impact of CIPN on cancer treatment outcomes and patients' psychosocial functioning and quality of life. Lisocabtagene maraleucel (liso-cel) for treatment of second-line (2L) transplant noneligible (TNE) relapsed/refractory (R/R) aggressive large B-cell non-Hodgkin lymphoma (NHL): Updated results from the PILOT study. Previous pilot data suggested that venlafaxine could prevent acute and chronic oxaliplatin-related neuropathy. 809 Followers, 675 Following, 29 Posts - See Instagram photos and videos from nina (@nina.wagner14) Post-transplant lymphoproliferative disorder (PTLD) after solid organ transplant (SOT): A multicenter real world analysis (RWA) of 877 patients (pts) treated in the modern era. Venlafaxine to prevent oxaliplatin-induced neuropathy? Serving Niederoesterreich, Oberoesterreich, Wien, Burgenland, Steiermark, Kaernten, Salzburg, Tirol. Assegnazione. Objectives: Explore Nina Woolley Wagner's 170 photos on Flickr! Preliminary results of PI3Kδ inhibitor idelalisib (GS-1101) treatment in combination with everolimus, bortezomib, or bendamustine/rituximab in patients with previously treated mantle cell lymphoma (MCL). Results of a phase III randomized, controlled study evaluating the efficacy and safety of idelalisib (IDELA) in combination with ofatumumab (OFA) for previously treated chronic lymphocytic leukemia (CLL). Final results of a phase I study of idelalisib, a selective inhibitor of phosphatidylinositol 3-kinase P110δ (PI3Kδ), in patients with relapsed or refractory mantle cell lymphoma (MCL). Hey all, my name is Nina Hunter and I provide videography and photo shoots. confronto: Nina Stojanovic vs. Stephanie Wagner 10.07.2019 - W60 Versmold Scopri Sconti e Spedizione con Corriere Gratuita! Hospices Civils de Lyon (Centre Hospitalier Universitaire de Lyon), University of Texas MD Anderson Cancer Center, Centre Hospitalier Universitaire de Clermont-Ferrand, Outcomes of patients with up to 6 years of follow-up from a phase 2 study of idelalisib for relapsed indolent lymphomas, Retrospective Analysis of the Impact of Adverse Event–Triggered Idelalisib Interruption and Dose Reduction on Clinical Outcomes in Patients With Relapsed/Refractory B-Cell Malignancies, Allogeneic Transplantation for Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia with Post-Transplantation Cyclophosphamide: Assessing the Importance of Conditioning Regimen, Donor Choice, and Tyrosine Kinase Inhibitor Use, Outcomes of Patients with Limited-Stage Plasmablastic Lymphoma, Reduced-Intensity Induction with Dasatinib Vs. Hypercvad + 2nd Generation TKIs with MRD-Guided Follow-up Therapy Leads to Comparable Rates of MRD-Negative Remission While Reducing Transfusions and Neutropenia in Ph+ ALL, Assessing Early Supportive Care Needs Among Son or Daughter Haploidentical Transplantation Donors, Shortened-Duration Immunosuppressive Therapy after Nonmyeloablative, Related HLA-Haploidentical or Unrelated Peripheral Blood Grafts and Post-Transplantation Cyclophosphamide. Background Dose-adjusted EPOCH-R compared with R-CHOP as frontline therapy for diffuse large B-cell lymphoma: Clinical outcomes of the Phase III intergroup trial alliance/CALGB 50303, DYNAMO: A Phase II Study of Duvelisib (IPI-145) in Patients With Refractory Indolent Non-Hodgkin Lymphoma, Outcome of Patients with Aggressive B Cell Lymphomas Who Receive Second-Line Salvage Immunochemotherapy Following Treatment Failure of Intensive First-Line Immunochemotherapy, Checkpoint Blockade Therapy May Sensitize Aggressive and Indolent Non-Hodgkin Lymphoma to Subsequent Therapy, Impact of Rituximab Infusion Reactions on Clinical Outcomes in Patients with Diffuse Large B-Cell Lymphoma, Sustained Disease Control for Adult Patients with Relapsed or Refractory Diffuse Large B-Cell Lymphoma: An Updated Analysis of Juliet, a Global Pivotal Phase 2 Trial of Tisagenlecleucel, Prognostic and Immune-Related Factors for Response to Duvelisib in the Phase 2 DYNAMOTM Clinical Trial in iNHL, Survival Outcomes Following Idelalisib Interruption in the Treatment of Relapsed or Refractory Indolent Non-Hodgkin's Lymphoma and Chronic Lymphocytic Leukemia, Checkpoint Blockade Therapy May Sensitize Hodgkin Lymphoma to Subsequent Therapy, Immune checkpoint inhibitors as a bridge to allogeneic transplantation with posttransplant cyclophosphamide, Abstract CT110: Clinical pharmacology of tisagenlecleucel (CTL019) in patients with relapsed/refractory (r/r) diffuse large B-cell lymphoma (DLBCL), Minimal activity of nanoparticle albumin-bound (nab) paclitaxel in relapsed or refractory lymphomas: results of a phase-I study, High frequency of identical clonal immunoglobulin DNA in pre-treatment tumor and plasma from untreated patients with HIV-associated lymphoma: prospective multicenter trial of the AIDS malignancies consortium (AMC 064), A Phase I/II Trial of Panobinostat in Combination With Lenalidomide in Patients With Relapsed or Refractory Hodgkin Lymphoma, Efficacy and safety of idelalisib in combination with ofatumumab for previously treated chronic lymphocytic leukaemia: an open-label, randomised phase 3 trial, Efficacy and safety of idelalisib in patients with relapsed, rituximab- and alkylating agent-refractory follicular lymphoma: A subgroup analysis of a phase 2 study, Combinations of idelalisib with rituximab and/or bendamustine in patients with recurrent indolent non-Hodgkin lymphoma, Dynamo: A Phase 2 Study Demonstrating the Clinical Activity of Duvelisib in Patients with Relapsed Refractory Indolent Non-Hodgkin Lymphoma, Comparison of oxaliplatin and paclitaxel-induced neuropathy (Alliance A151505). Iscriviti a Facebook per connetterti con Nina Wagner e altre persone che potresti conoscere. Idelalisib, a selective oral inhibitor of PI3Kd, demonstrated considerable clinical activity as monotherapy in recurrent (Flinn, Blood 2014) or refractory iNHL subjects (Gopal, NEJM 2014). Inhibition by Idelalisib in Patients with Relapsed Indolent Lymphoma, Chemo-Immunotherapy Combination Of Idelalisib With Bendamustine/Rituximab Or Chlorambucil/Rituximab In Patients With Relapsed/Refractory CLL Demonstrates Efficacy and Tolerability, Mature Response Data From a Phase 2 Study Of PI3K-Delta Inhibitor Idelalisib In Patients With Double (Rituximab and Alkylating Agent)-Refractory Indolent B-Cell Non-Hodgkin Lymphoma (iNHL), Idelalisib, a Selective Inhibitor Of PI3Kδ, In Combination With Bendamustine, Fludarabine Or Chlorambucil In Patients With Relapsed Or Refractory (R/R) Chronic Lymphocytic Leukemia (CLL), High Incidence of Methotrexate Associated Renal Toxicity in Patients with Lymphoma: A Retrospective Analysis. Service vor Ort, viele Testsättel und eine eigene Sattlerei runden unser Angebot ab. While anthracycline-based treatment can cure diffuse large B-cell lymphoma, most patients over age 80 do not receive doxorubicin due to toxicity concerns. Patients had a median (range) age of 64 (32-91) years, 34 (53%) had bulky disease (≥1 lymph nodes ≥5 cm), and 37 (58%) had refractory disease. Alisertib is a novel oral AAK inhibitor without adverse safety signals in early-phase studies that demonstrated preliminary activity in T-cell lymphoma. The primary outcome of interest was overall survival. We previously presented evidence from a single institution study that rearranged immunoglobulin (Ig) DNA could frequently be detected by clone specific PCR in HIV patients (pts) with lymphoma (Blood 2011;117:4860-2). Idelalisib is a selective, oral inhibitor of PI3Kδ that has been previously shown to be safe and tolerable and has demonstrated considerable activity as monotherapy or in combination with other agents in patients with relapsed/... Introduction Der AVEDA Salon NI`NA steht für Höchste Qualität, Sinn für stilvolle Schnitte, zeitlose Klassiker, Offenheit und Trendbewusstsein. Im Profil von Nina Wagner sind 7 Jobs angegeben. 127 Hedge RdAikenSC 29801phone: 803.649.2766mysaddle.cominfo@mysaddle.com, Niederoesterreich, Oberoesterreich, Wien, Burgenland, Steiermark, Kaernten, Salzburg, Tirol. PI3K-delta signaling is critical for proliferation, survival, homing and tissue retention of malignant B cells. Ann Oncol. The product label indicates that 3 patients who were treated with BV developed progressive multifocal leukoencephalopathy (PML), a frequently fatal JC virus-... BACKGROUND 2010; 21:851-854). MZL comprises 5-17% of all non-Hodgkin lymphomas in adults (Cervetti et al. This report described the 5-year follow-up results. To confirm and extend our results, we studied... BACKGROUND: PI3Kδ signaling is critical for the proliferation and survival as well as for homing and tissue retention of malignant B cells. Sorry, you need to be a researcher to join ResearchGate. ServingNiederoesterreich, Oberoesterreich, Wien, Burgenland, Steiermark, Kaernten, Salzburg, Tirol. Phosphatidylinositol-3-kinase delta (PI3K) mediates B-cell receptor signaling and microenvironmental support signals that promote the growth and survival of malignant B lymphocytes. A phase 2 study of inotuzumab ozogamicin in patients with indolent B-cell non-Hodgkin lymphoma refractory to rituximab alone, rituximab and chemotherapy, or radioimmunotherapy, Post-ibrutinib outcomes in patients with mantle cell lymphoma, A Phase I Trial of Brentuximab Vedotin in Combination with Lenalidomide in Relapsed or Refractory Diffuse Large B-Cell Lymphoma, Idelalisib Monotherapy and Durable Responses in Patients with Relapsed or Refractory Small Lymphocytic Lymphoma (SLL), Idelalisib Monotherapy and Durable Responses in Patients with Relapsed or Refractory Marginal Zone Lymphoma (MZL), Outcomes with R-CEOP for R-CHOP-ineligible patients with diffuse large B-cell lymphoma are highly dependent on cell of origin, Mature Follow-up from a Phase-2 Study of PI3K-Delta Inhibitor Idelalisib in Patients with Double (Rituximab and Alkylating agent)-Refractory Indolent B-Cell Non-Hodgkin Lymphoma (iNHL), Clinical Course of Oxaliplatin-Induced Neuropathy: Results From the Randomized Phase III Trial N08CB (Alliance), MC11C4: a pilot randomized, placebo-controlled, double-blind study of venlafaxine to prevent oxaliplatin-induced neuropathy, Outcomes of transformed follicular lymphoma in the modern era: A report from the National LymphoCare Study (NLCS), Phase II Intergroup Trial of Alisertib in Relapsed and Refractory Peripheral T-Cell Lymphoma and Transformed Mycosis Fungoides: SWOG 1108. Lenalidomide (Revlimid®) is an approved anti-neoplastic therapy for multiple myeloma and myelodysplastic syndrome with del(5q). GS-1101 is an orally bioavailable, small-molecule inhibitor of PI3Kδ that has shown considerable monotherapy activity when given at dose levels of ≥100 mg BID in patients with heavily pretreated indolent non-Hodgkins lymphoma (iNHL). 21 talking about this. Nina WAGNER-JOHNSTON of Washington University in St. Louis, Missouri (WUSTL , Wash U) | Read 126 publications | Contact Nina WAGNER-JOHNSTON Relapsed or refractory (rel/ref) classical Hodgkin lymphoma (cHL) remains a clinical challenge with limited effective treatments after high dose therapy with autologous stem cell transplantation (ASCT). Idelalisib is a first-in-class, selective, oral inhibitor of PI3Kδ that has shown monotherapy activity in recurrent MCL (Kahl, ICML 20... 7017 Hunter Wagner Imagery, Little Rock, Arkansas. Nina Wagner Introduction Initial response rate of 38% was reported previously in iNHL... 8519 Acquista Libri in lingua straniera di Wagner Nina su Libreria Universitaria, oltre 8 milioni di libri a catalogo. Nina Stemme (born May 11, 1963 in Stockholm) is an opera singer known for her warm, solid spinto soprano voice, with some qualities of a dramatic soprano. Background: PI3K-delta signaling is critical for activation, proliferation and survival of B cells and plays a role in homing and retention in lymphoid tissues. Idelalisib (GS-1101) is a first-in-class, selective, oral inhibitor of PI3Kδ. PI3Kδ signaling is hyperactive in many B-cell malignancies. Idelalisib efficacy and safety in follicular lymphoma patients from a phase 2 study. Der AVEDA Salon NI`NA steht für Höchste Qualität, Sinn für stilvolle Schnitte, zeitlose Klassiker, Offenheit und Trendbewusstsein. SLL is characterized by the accumulation of small, mature lymphocytes in lymph nodes without elevation of peripheral blood lym... Background: MZL, a group of indolent B-cell lymphomas, arises from marginal zone B cells present in lymph nodes and/or extranodal tissues. Nina Wagner. Methods and Patients In... Join ResearchGate to find the people and research you need to help your work. A systematic literature search identified relevant, randomized controlled trials (RCTs) for the treatment of CIPN. In total, 241 patients who were newly diagnosed with cHL between January 2000 and December... Chemotherapy-induced peripheral neuropathy (CIPN) is a common and debilitating condition associated with a variety of chemotherapeutic agents. Ich betreue Österreichweit Profis wie auch Freizeitreiter die absolut überzeugt sind von Custom Sätteln. © 2008-2021 ResearchGate GmbH. The addition of rituximab to CHOP has improved the overall survival of patients with diffuse large B-cell lymphoma (DLBCL); however, approximately 30% of patients will relapse. Ich betreue Österreichweit Profis wie auch Freizeitreiter die … The objective of this study was to compare the outcomes of patients with classical Hodgkin lymphoma (cHL) who achieved complete remission with frontline therapy and then underwent either clinical surveillance or routine surveillance imaging.METHODS Idelalisib (GS-1101) is a first-in-class, selective, oral inhibitor of PI3Kδ that reduces proliferation, enhances apoptosis... 8500 Incidence of large granular lymphocytosis (LGL) in patients with late cytopenias after allogeneic blood or marrow transplantation (AlloBMT). Background: PI3K-delta signaling is critical for activation, proliferation and survival of B cells, and is hyperactive in many B-cell malignancies. Idelalisib (IDELA) is a potent and selective orally administered inhibitor of PI3Kδ with demonstrated activity in patients with R/R CLL... Abstract High dose methotrexate (HDMTX), defined by doses of methotrexate (MTX) ≥ 1g/m2, is a widely used regimen known to cause renal toxicity. Particularly, once iNHL becomes “double-refractory” to rituximab + alkylating agents, there are few data available on beneficial therapeutic options and development of novel th... Background Background: PI3K-delta is critical for activation, proliferation and survival of B cells and plays a role in homing and retention in lymphoid tissues. Cerdulatinib (PRT062070): A dual SYK/JAK inhibitor in patients with relapsed/refractory b-cell malignancies—Pharmacokinetic and pharmacodynamic outcomes with twice-daily (BID) vs once-daily (QD) dosing. Auf LinkedIn können Sie sich das vollständige Profil ansehen und mehr über die Kontakte von Nina Wagner und Jobs bei ähnlichen Unternehmen erfahren. Introduction The reported incidence of renal toxicity in osteosarcoma patients is 1.8%, but the incidence in hematologic malignancies is not well characterized. Despite unprecedented clinical activity in mantle cell lymphoma (MCL), primary and acquired resistance to ibrutinib is common. Kaum eine andere Marke bietet solch eine Vielfalt an Möglichkeiten für Pferd UND Reiter. Informazioni sul coronavirus: Riportiamo la vostra attenzione sul divieto di visita e sull’obbligo di indossare la mascherina dai partire a 6 anni in ogni area della clinica. Primary outcome was safety and dose-limiting toxicity (DLT). Methods: This phase I study evaluated idelalisib continuously given a... 3645 Initial response rate of 42% was previously reported in... 8501 Secondary outcomes i... Introduction: Rituximab-alkylator combinations are the standard therapies for patients (pts) with iNHL, however, refractory disease nearly uniformly develops. The outcomes and ideal management of patients that experience ibrutinib failure are unclear. We performed a retrospective cohort study of all patients with MCL that experienced disease progression while receiving ibrutinib... Background: 8 mg/m(2) intravenously on a 28-d cycle for a planned 4-8 cycles. Nina Stemme (born May 11, 1963 in Stockholm) is an opera singer known for her warm, solid spinto soprano voice, with some qualities of a dramatic soprano. Nina Wagner è su Facebook. Pharmacokinetics and pharmacodynamics of the dual syk/jak inhibitor PRT062070 (cerdulatinib) in patients with advanced B-cell malignancies. Iscriviti a Facebook per connetterti con Nina Wagner e altre persone che potresti conoscere. Sehen Sie sich das Profil von Nina Wagner im größten Business-Netzwerk der Welt an. Patient-reported outcomes data from a phase 2 study of idelalisib in patients with refractory indolent B-cell non-Hodgkin lymphoma (iNHL). Stem cell transplantation (SCT) provides a second chance at cure, but the prognosis for patients who are not candidates for SCT or who have refractory disease is... Background: SLL, a subtype of indolent non-Hodgkin's Lymphoma (iNHL), is considered the tissue equivalent of chronic lymphocytic leukemia (CLL); each disease is considered a clinical variation of the same biological entity. In this retrospective study of 649 cycles of HDMTX in 194... 7003 Nina Wagner. Idelalisib is a first-in-class, selective, oral inhibitor of PI3Kδ that has shown considerable monotherapy activity in recurrent iNHL (Kahl, ICML 2011), as well as combination therapy (Fowler, ASCO... 8526 Prognostic value of interim FDG-PET in diffuse large cell lymphoma: results from the CALGB 50303 Clinical Trial, Tisagenlecleucel cellular kinetics, dose, and immunogenicity in relation to clinical factors in relapsed/refractory DLBCL, Poor outcomes for double-hit lymphoma patients treated with curative-intent second-line immunochemotherapy following failure of intensive front-line immunochemotherapy, Correlative Analyses of Patient and Clinical Characteristics Associated with Efficacy in Tisagenlecleucel-Treated Relapsed/Refractory Diffuse Large B-Cell Lymphoma Patients in the Juliet Trial, Correlation of Bridging and Lymphodepleting Chemotherapy with Clinical Outcomes in Patients with Relapsed/Refractory Diffuse Large B-Cell Lymphoma Treated with Tisagenlecleucel, Safety and Anti-Tumor Activity Study of Loncastuximab Tesirine and Ibrutinib in Diffuse Large B-Cell or Mantle Cell Lymphoma, Allogenic Stem Cell Transplantation for Secondary CNS Lymphoma: A Retrospective Review of 21 Patients, Long-Term Follow-up of Idelalisib Monotherapy in Patients with Double-Refractory Marginal Zone Lymphoma or Lymphoplasmacytic Lymphoma/ Waldenstrom's Macroglobulinemia, Impact of Idelalisib Treatment Interruption with or without Dose Reduction on Outcomes in Relapsed / Refractory Indolent Non-Hodgkin's Lymphoma and Chronic Lymphocytic Leukemia, A Phase IB Study of Blinatumomab (blina) in Patients with B Cell Acute Lymphoblastic Leukemia (ALL) and B-Cell Non-Hodgkin Lymphoma (NHL) As Post-Allogeneic Blood or Marrow Transplant (allo-BMT) Remission Maintenance, Impact of Tisagenlecleucel Chimeric Antigen Receptor (CAR)-T Cell Therapy Product Attributes on Clinical Outcomes in Adults with Relapsed or Refractory Diffuse Large B-Cell Lymphoma (r/r DLBCL), Survival Outcomes Following Idelalisib Interruption in the Treatment of Relapsed or Refractory Indolent Non-Hodgkin’s Lymphoma and Chronic Lymphocytic Leukemia, Outcomes in patients with aggressive B‐cell non‐Hodgkin lymphoma after intensive frontline treatment failure. Iscriviti a Facebook per connetterti con Nina Wagner e altre persone che potresti conoscere. This study evaluated this practice, as patients age 80 and older are largely excluded from clinical trials. Main navigation. U.S. Intergroup phase II trial (SWOG 1108) of alisertib, an investigational aurora A kinase (AAK) inhibitor, in patients with peripheral T-cell lymphoma (PTCL; NCT01466881). A total of 551 postmenopausal women with breast cancer... For patients with limited prognosis, some medication risks may outweigh the benefits, particularly when benefits take years to accrue; statins are one example. Preliminary results of PI3K{delta} inhibitor idelalisib (GS-1101) treatment in combination with everolimus, bortezomib, or bendamustine/rituximab in patients with previously treated mantle cell lymphoma (MCL), Combinations of the Phosphatidylinositol 3-Kinase-Delta (PI3Kδ) Inhibitor Gs-1101 (CAL-101) with Rituximab and/or Bendamustine Are Tolerable and Highly Active in Previously Treated, Indolent Non-Hodgkin Lymphoma: Results From a Phase I Study, Combinations of the Selective Phosphatidylinositol 3-Kinase-Delta (PI3Kdelta) Inhibitor GS–1101 (CAL-101) with Rituximab and/or Bendamustine Are Tolerable and Highly Active in Patients with Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL): Results From a Phase I Study, A Phase 2 Multicenter Study of Continuous Dose Lenalidomide in Relapsed or Refractory Classical Hodgkin Lymphoma, A phase I/II study of the selective phosphatidylinositol 3-kinase -delta (PI3K delta) inhibitor, GS-1101 (CAL-101), with ofatumumab in patients with previously treated chronic lymphocytic leukemia (CLL), Department of Hematology and Medical Oncology. Join Facebook to connect with Nina Wagner and others you may know. Primary outcomes included incidence and severity... Idelalisib (GS-1101, CAL-101), an oral inhibitor of phosphatidylinositol 3-kinase-δ, was evaluated in a phase I study in 64 patients with relapsed indolent non-Hodgkin lymphoma (iNHL). 35 were here. Country Austria City Wolfsbach. Introduction. 36 were here. PI3K-delta signaling is critical for activation, prolifera... Background: Individuals with HIV are at increased risk for B cell lymphoid malignancy. Nina Wagner è su Facebook. Idelalisib is a first-in-class, targeted, highly selective, oral inhibitor of PI3Kδ with considerable activity as monotherapy and in combination with R in patients with relapsed/refractory CLL, and was recently... Introduction: PI3K-delta signaling is critical for activation, proliferation and survival of B cells, and is hyperactive in many B-cell malignancies. Updated results of a phase III randomized, controlled study of idelalisib in combination with ofatumumab for previously treated chronic lymphocytic leukemia (CLL). View the profiles of people named Nina Wagner. This Phase 1 combination study has evalu... 1623 This Phase 1... 191 Background: Signals through PI3K-delta regulate activation, proliferation and survival of B cells, critically influence homing and retention of B cells in lymphoid tissues, and are hyperactive in many BEcell malignancies. Vezi profilurile persoanelor care poartă numele de Nina Wagner. All rights reserved. Most iNHL will eventually become refractory to current therapies. GS-1101 is an orally bioavailable, small-molecule inhibitor of PI3Kdelta that has shown considerable monotherapy activity when given at dose levels of 3100 mg BID in patients with heavily pretreated CLL. Name Nina Wagner. University students and faculty, institute members, and independent researchers, Technology or product developers, R&D specialists, and government or NGO employees in scientific roles, Health care professionals, including clinical researchers, Journalists, citizen scientists, or anyone interested in reading and discovering research. Fashion Production and Operations Assistant based in Amsterdam. PI3Kδ signaling is hyperactive in many B-cell malignancies. In a phase 1 study, idelalisib, an orally active selective PI3K inhibitor, showed antitumor activity in patients with previously treated indolent non-Hodgkin... Background See what Nina Wagner (NinWagna) has discovered on Pinterest, the world's biggest collection of ideas. Tolerability and activity of combinations of the PI3Kδ inhibitor idelalisib (GS-1101) with rituximab and/or bendamustine in patients with previously treated, indolent non-Hodgkin lymphoma (iNHL): Updated results from a phase I study. Update on a phase I study of the selective PI3Kδ inhibitor idelalisib (GS-1101) in combination with rituximab and/or bendamustine in patients with relapsed or refractory CLL. About. Methods and Patients Some partners do not ask for your consent to process your data, instead, they rely on their legitimate business interest. Toxicity of dose-intensive regimens used for Burkitt lymphoma (BL) prompted modification of the CODOX-M/IVAC regimen for HIV+ patients.
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